Lab Culture

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Sue Biggins

I’m a: biologist

My research: Dr. Sue Biggins directs the Basic Sciences Division and conducts research on how cells sort chromosomes, the molecules that carry DNA. Every time a cell divides, it must copy each chromosome and make sure that both daughter cells inherit exactly one copy of each. The wrong number of chromosomes is the most common chromosomal abnormality in cancers and the cause of birth defects and other diseases.

Dr. Biggins' work focuses on understanding how cells regulate division and chromosome movement during cell division to ensure accurate self-renewal, proliferation and development. Her lab takes an interdisciplinary approach that combines biochemical, biophysical, cell biological, genetic and structural approaches using yeast and human cells as model systems. Dr. Biggins led the team that originally isolated the kinetochore, the large molecular machine that coordinates chromosome sorting, from yeast cells. This accomplishment paved the way for critical new findings, including the role that tension plays in chromosome sorting.

What do you typically eat for breakfast? yogurt parfait

What is your favorite type of cuisine to cook? dessert - I bake everyone in my lab a cake for their birthday

What is your favorite snack or candy? malt balls

What is your favorite spice? burlap and Barrel Royal cinnamon

What is one food you absolutely dislike? liver

My 4 dream scientist dinner companions:

Angelika Amon
Barbara McClintock
Raychelle Burks
Rosalind Franklin

Biggins Lab


Sue’s Recipe