Lab Culture

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Barbara Mellone

I’m a: biologist, geneticist

My research: During cell division, chromosomes must be accurately segregated to daughter cells. Errors during this process are an underlying cause of genetic abnormalities such as birth defects and cancer progression in humans. Our lab focuses on the role of the centromere, an essential locus that is required for chromosome capture and poleward movement by spindle microtubules. Our goal is to understand how centromeres are specified and inherited and how cells ensure that one-and only one- centromere is present on each chromosome. We are also interested in the evolutionary forces that shape centromere-binding proteins and centromeric DNA. We use the simple fruit fly Drosophila melanogaster as a model, taking full advantage of its genetic tools, genomic data, and beautiful cell biology.

What do you typically eat for breakfast? coffee

What is your favorite type of cuisine to cook? anything on the grill

What is your favorite snack or candy? salty pistachios

What is your favorite spice? does Parmigiano count? If not, black pepper

What is one food you absolutely dislike? anything with fennel seeds

My 4 dream scientist dinner companions:

Barbara McClintock
Nettie Stevens
Rosalind Franklin
Rita Levi Montalcini


Barbara’s Recipe